Myofibroblastic Tumours; A Case Report of Nodular Fasciitis

Main Article Content

Mehmet Ozgel


Aims: Nodular fasciitis (NF) is a benign, reactive proliferation of fibroblasts in the subcutaneous tissues and commonly associated with the deep fascia. It is caused the lesion to be misdiagnosed as sarcoma due to this fibroblastic proliferation. Early surgical excision can be performed for both diagnostic and therapeutic purposes. So we can save the patient from both misdiagnosis and latent malignancy. In this report, we presented slower-growing NF on the chest wall according to in oral cavity.

Presentation: A 37-year-old female patient had chest pain and dyspnea. A mass of 2 cm in diameter was detected and removed on the chest wall. She was discharged early period after the operation.

Discussion: Nodule is most commonly seen single, solid and palpable. Curative excision can be performed in both diagnostic and treatment. The recurrence rate is around 1% from it. If it would relapse, the diagnosis should be revised.

Solitary nodule, chest wall, nodular fasciitis.

Article Details

How to Cite
Ozgel, M. (2020). Myofibroblastic Tumours; A Case Report of Nodular Fasciitis. Asian Journal of Case Reports in Surgery, 3(1), 12-15. Retrieved from
Case Study


Dayan D, Nasrallah V, Vered M. Clinicopathologic correlations of myofibroblastic tumours of the oral cavity: Nodular fasciitis. J Oral Pathol Med. 2005;34(7):426-35.

Boyd Z, Krad N, Nicklaus P, Lowe L. Midfacial degloving approach to myxoid type nodular fasciitis of the maxilla in a 16-month-old female. Internet Journal of Pediatrics & Neonatology. 2009;10(1):9.

Xu-Yong L, Liang W, Yong Z, Shun-Dong D, En-Hua W. Variable Ki67 proliferative index in 65 cases of nodular fasciitis, compared with fibrosarcoma and fibromatosis. Diagnostic Pathology. 2013; 8:50.

Leung L, Shu S, Chan A, Chan M, Chan C. Nodular fasciitis: MRI appearance and literature review. Skeletal. Radiol. 2002; 31(1):9-13.

Patel NR, Chrisinger JSA, Demicco EG, Sarabia SF, Reuther J, Kumar E, Oliveira AM, Billings SD, Bovée JVMG, Roy A, Lazar AJ, Lopez-Terrada DH, Wang WL. USP6 activation in nodular fasciitis by promoter-swapping gene fusions. Mod Pathol. 2017;30(11):1577-1588.

Kim ST, Kim HJ, Park SW, et al. Nodular fasciitis in the head and neck: CT and MR imaging findings. AJNR Am J Neuroradiol. 2005;26:2617-2623.

Graadt van Roggen JF, Hogendoorn PC, Fletcher CD. Myxoid tumours of soft tissue. Histopathology. 1999;35:291-312.

Montgomery EA, Meis JM. Nodular fasciitis. Its morphologic spectrum and immunohistochemical profile. Am J Surg Pathol. 1991;15:942-948.

Rani D, Gupta A. Cytological Diagnosis and Misdiagnosis of Nodular Fasciitis. Rani D, Gupta A. Cytological diagnosis and misdiagnosis of nodular fasciitis. J Cytol. 2019;36:196-9.

Lara de Carli M, Sá Fernandes K, Pinto DS, Witzel AL, Martins MT. Nodular fasciitis of the oral cavity with partial spontaneous regression (Nodular Fasciitis). Head Neck Pathol. 2013;7(1):69–72.

Di Serafino M, Maurea S, Vallone G. Nodular fasciitis of the chest: case report of a rare presentation. Musculoskelet Surg. 2011;95:251–312.

Suh JH, Yoon JS, Park CB. Nodular fasciitis on the chest wall in a teenager: A case report and review of the literature. J Thorac Dis. 2014;6:E108–10.

Yanagisawa A, Okada H. Nodular fasciitis with degeneration and regression. J Craniofac Surg. 2008;19(4):1167-70.

Hideyuki Kinoshita, Tsukasa Yonemoto, Hiroto Kamoda, et al. Giant Protruding Nodular Fasciitis of the Anterior Chest Wall Clinically Mimicking a Soft Tissue Sarcoma, Case Reports in Orthopedics. 2019;5.
[Article ID 4174985]