Neurofibroma Arising in Ectopic Breast Tissue: A Unique Case Report

Main Article Content

Cammarata Roberto
Cammarata Antonio


Neurofibromas are benign nerve sheath tumours which occur in the dermis or subcutis with a variable distribution on the body surface. Accessory breast tissue results from incomplete involution of the embryologic mammary ridge. We report a case of a 63-year postmenopausal multiparous woman who presented to our department with a lump in the lower left abdominal quadrant near a supernumerary nipple. An abdominal ultrasound confirmed the presence of a 20mm mass and describes it as a hypo-anechoic neoformation below the accessory nipple in the context of likely breast parenchyma. A large local excision of the lesion was therefore planned. A final histologic diagnosis of neurofibroma arising in accessory breast tissue was made. This case report describes for the first time a case of a neurofibroma arising on ectopic breast tissue.

Neurofibroma, breast, ectopic breast tissue.

Article Details

How to Cite
Roberto, C., & Antonio, C. (2020). Neurofibroma Arising in Ectopic Breast Tissue: A Unique Case Report. Asian Journal of Case Reports in Surgery, 5(4), 28-35. Retrieved from
Case Study


Goldblum J, Weiss S, Folpe AL. Enzinger and Weiss’s Soft Tissue Tumours, in Enzinger and Weiss’s Soft Tissue Tumours 4th ed., Elsevier; 2014.

Shao C, Zhang J, Ling F, Fu J, Huang Z. Giant solitary neurofibroma in the breast: A case report and review of the literature. Cancer Treat. Commun. 2015;4:19–22.

Sherman JE, Smith JW. Neurofibromas of the breast and nipple-areolar area. Ann. Plast. Surg. 1981;7(4):302–307.

Jeyaretna DS, Oriolowo A, Smith MEF, Watkins RM. Solitary neurofibroma in the male breast. 2007;3:3–5.

Laky D, Petraru DM, Ancar V, Kelemen J. Giant neurofibroma of the pectoral region including the breast. Case report. Rom. J. Morphol. Embryol. = Rev. Roum. Morphol. Embryol. 1990;36(3–4):213– 215.

Narayan AS, Rao KP. Neurofibroma of the breast. J. Indian Med. Assoc. 1968;50(8):375–376.

Lim HS, et al., “Sonographic findings of accessory breast tissue in axilla and related diseases,” Journal of Ultrasound in Medicine; 2017.

Bland KI, Copeland EM, Klimberg VS, Gradishar WJ. The Breast: Comprehensive Management of Benign and Malignant Diseases; 2017.

Kayava Y. The proportions of supernumerary nipples in the Finnish population. Duodecim. 1915;31:143– 170.

Youn HJ, Jung SH. Accessory breast carcinoma. Breast Care; 2009.

Amaranathan A, Balaguruswamy K, Bhat RV, Bora MK. An Ectopic Breast Tissue Presenting with Fibroadenoma in Axilla. Case Rep. Surg; 2013.

Oshida K, et al. Phyllodes tumor arising in ectopic breast tissue of the axilla. Breast Cancer; 2003.

Rodriguez FJ, Folpe AL, Giannini C, Perry A. Pathology of peripheral nerve sheath tumors: Diagnostic overview and update on selected diagnostic problems. Acta Neuropathologica; 2012.