Asian Journal of Case Reports in Surgery

Abstract

Primary congenital glaucoma (PCG) is a rare eye disease that affected 0.01-0.04% of total blindness. The disease is usually manifested at birth or before 3 years of age. The incidence of PCG is different in different populations and is approximately 1 in 10,000 births in western developed countries. The diagnosis by the age of 6 months is about 60%, and 80% within the first year of life. Males is common (about 65%), and the involvement is usually bilateral is about 70%. The disease is family in 10-40% of cases with variable penetrance (40-100%). Patients with a familial pattern usually show a recessive pattern with incomplete or variable penetrance and possibly multifactorial inheritance. PCG relates an isolated maldevelopment of the trabecular that can raise the IOP. PCG is the most common form of developmental glaucoma. The condition is typically bilateral and 30% of the cases may be unilateral. Surgical treatment with trabeculotomy and medical therapy is a supportive role. The prognosis for children with PCG is quite variable, with some achieving good vision thanks to scientific advances, while others go blind especially in a developing country. So the quality of life in these patients is very necessary. Our 2 cases of PCG on a mother and her son in one family are reported with some satisfying results in the quality of life.