Primary Neuroendocrine Breast Carcinoma (NEBC): A Case Report
Rangra Gayatri
Department of Surgery, ASMC Kaushambi, India.
Singhal Basant Mohan *
Department of Surgical Oncology, M L N Medical College, Prayagraj, India.
Kewlani Vishal
Department of Surgery, M L N Medical College, Prayagraj, India.
Yadav Dev Kumar
Department of Radiation Oncology, M L N Medical College, Prayagraj, India.
*Author to whom correspondence should be addressed.
Abstract
Primary Neuroendocrine Breast Carcinoma (NEBC) is a rare tumor with an incident rate of <0.1% of Breast Cancers and <1% of all neuroendocrine neoplasms. This case report describes a 60-year-old female patient with NEBC of the left breast with no axillary lymphadenopathy or metastasis at initial presentation. The tumor cells were positive for neuroendocrine markers, a highKi67 proliferation index and negative for ER/PR and Her2neu. Breast neuroendocrine tumors are a rare heterogenous group of tumors and further studies are needed to understand its’ presentation and establish effective management strategies.
Keywords: Neuroendocrine neoplasms, neuroendocrine carcinoma, breast cancer, NEBC, NECB