A Rare Case of Pediatric Lipoblastoma: Diagnostic and Surgical Insights

Aditya Mukim

Gujarat Cancer Research Institute, Ahmedabad, India.

Gautami Joshi *

Gujarat Cancer Research Institute, Ahmedabad, India.

Mohit Sharma

Gujarat Cancer Research Institute, Ahmedabad, India.

Shashank Pandya

Gujarat Cancer Research Institute, Ahmedabad, India.

*Author to whom correspondence should be addressed.


Abstract

Aims: Lipoblastoma occurs mostly in young children and is extremely rare in adults, with most cases are found in children less than 3 years of age. It can present with a rapid growth rate, exerting pressure on surrounding structures or be slow growing and more difficult to detect.

Case Presentation: A 3 year old female was brought to OPD with complaints of a swelling over lower back on right side since 3 months.

A computed tomography of thorax was done that was suggestive of a well defined fat density lesion in intermuscular plane of posterior abdominal wall of right lumbar region. A core needle biopsy was suggestive of a lipomatous neoplasm. A final immunohistochemistry was suggestive of a benign adipocytic tumor.

A wide local excision incorporating the scar of biopsy was carried out. A gross margin of 1 cm was taken on all sides.

Discussion: Lipoblastoma arise from abnormal proliferation of immature fat cells. Histologically there is an overlap between lipoblastoma and myxoid liposarcoma. Lipoblastomas appear as rapidly growing, localized well-circumscribed masses. Lipoblastomatosis is a more severe and diffuse form and has a higher recurrence rate due to infiltrative characteristics.

The treatment of choice consists of complete surgical resection with free margins to prevent recurrence. A more conservative approach in children with large invasive lesions or lesions in locations like the extremities that would lead to mutilating surgical excision has been described.

Conclusion: Lipoblastoma is a poorly understood and uncommon soft tissue tumour in the infancy and early childhood.

Keywords: Myxoid liposarcoma, swelling, tomography, surgical excision


How to Cite

Mukim, Aditya, Gautami Joshi, Mohit Sharma, and Shashank Pandya. 2025. “A Rare Case of Pediatric Lipoblastoma: Diagnostic and Surgical Insights”. Asian Journal of Case Reports in Surgery 8 (1):246-52. https://doi.org/10.9734/ajcrs/2025/v8i1632.

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