Invasive Hemifacial Mycosis Mimicking Facial Malignancy: A Case Report

Oshiozimede Quincy AIGBONOGA *

Plastic and Reconstructive Unit, Irrua Specialist Teaching Hospital, Irrua/Ambrose Alli University, Ekpoma/ADIZA Hospital, Jattu, Edo State, Nigeria.

Oluwafemi Olasupo AWE

Plastic and Reconstructive Unit, Irrua Specialist Teaching Hospital, Irrua/Ambrose Alli University, Ekpoma, Edo State, Nigeria.

Orume Lucky ENEGBUYA

Department of Anatomic Pathology, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria.

Kerry AZEKE

Department of Anaesthesiology, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria.

Stella Nneka NGWU

Department of Anaesthesiology, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria.

Ewoigbe IKHUORIA

Department of Anaesthesiology, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria.

Charles IKHIFA

Department of Surgery, Irrua Specialist Teaching Hospital, Irrua Edo State, Nigeria.

Fidelis OZOBA

Department of Surgery, University of Benin Teaching Hospital, Benin, Edo State, Nigeria.

Miracle Onosetale EDOKPA

Department of Surgery, Asaba Specialist Hospital, Asaba, Delta State, Nigeria.

Unity Akugbe EHIJIE

Federal Medical Centre, Abeokuta, Ogun State, Nigeria.

*Author to whom correspondence should be addressed.


Abstract

Invasive facial fungal infections are confusing disease processes that can involve one, or more regions of the face, presenting with varied clinical features that mimic other clinical conditions that could range from benign disease conditions to malignancies. While typically exhibiting characteristic features of fungal disease, facial mycosis can sometimes present in an unusual manner, having improbable localization to different aspect of the face such as the eyelids, cheeks, ear, etc. We present a 75-year-old retired military man from the rural part of southern Nigeria who presented with left hemifacial growth and deformity, and ptosis of the left upper eyelid. Tissue biopsy analysis yielded Histoplasmosis which when treated with the use of oral and topical anti-fungal medications led to complete resolution of all presenting complaints.

Keywords: Fungal infections, medications, darling disease, mucous membrane


How to Cite

AIGBONOGA, Oshiozimede Quincy, Oluwafemi Olasupo AWE, Orume Lucky ENEGBUYA, Kerry AZEKE, Stella Nneka NGWU, Ewoigbe IKHUORIA, Charles IKHIFA, Fidelis OZOBA, Miracle Onosetale EDOKPA, and Unity Akugbe EHIJIE. 2025. “Invasive Hemifacial Mycosis Mimicking Facial Malignancy: A Case Report”. Asian Journal of Case Reports in Surgery 8 (2):401-6. https://doi.org/10.9734/ajcrs/2025/v8i2656.

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